Whole exome sequencing reveals NOTCH1 mutations in anaplastic large cell lymphoma and points to Notch both as a key pathway and a potential therapeutic target

HAEMATOLOGICA

Larose, H; Prokoph, N; Matthews, JD; Schlederer, M; Hogler, S; Alsulami, AF; Ducray, SP; Nuglozeh, E; Fazaludeen, MF; Elmouna, A; Ceccon, M; Mologni, L; Gambacorti-Passerini, C; Hoefler, G; Lobello, C; Pospisilova, S; Janikova, A; Woessmann, W; Damm-Welk, C; Zimmermann, M; Fedorova, A; Malone, A; Smith, O; Wasik, M; Inghirami, G; Lamant, L; Blundell, TL; Klapper, W; Merkel, O; Burke, GAA; Mian, S; Ashankyty, I; Kenner, L; Turner, SD, 2021: Whole exome sequencing reveals NOTCH1 mutations in anaplastic large cell lymphoma and points to Notch both as a key pathway and a potential therapeutic target. HAEMATOLOGICA 106(6), p. 1693 - 1704, doi: 10.3324/haematol.2019.238766

Research Groups:

• Medical Genomics - Šárka Pospíšilová

CEITEC authors:

• Dr. Suzanne Dawn Turner
• Prof. Šárka Pospíšilová, Ph.D.