Boris Tichý, Ph.D.

Publications that are part of the Web of Science database, possibly also other publications chosen by authors.

2021

• Aksoy, O; Pencik, J; Hartenbach, M; Moazzami, AA; Schlederer, M; Balber, T; Varady, A; Philippe, C; Baltzer, PA; Mazumder, B; Whitchurch, JB; Roberts, CJ; Haitel, A; Herac, M; Susani, M; Mitterhauser, M; Marculescu, R; Stangl-Kremser, J; Hassler, MR; Kramer, G; Shariat, SF; Turner, SD; Tichy, B; Oppelt, J; Pospisilova, S; Hartenbach, S; Tangermann, S; Egger, G; Neubauer, HA; Moriggl, R; Culig, Z; Greiner, G; Hoermann, G; Hacker, M; Heery, DM; Merkel, O; Kenner, L, 2021: Thyroid and androgen receptor signaling are antagonized by mu-Crystallin in prostate cancer. INTERNATIONAL JOURNAL OF CANCER 148(3), p. 731 - 747, doi: 10.1002/ijc.33332
• Kwik, M; Hainzl, S; Oppelt, J; Tichy, B; Koller, U; Bernardinelli, E; Steiner, M; Zara, G; Nofziger, C; Weis, S; Paulmichl, M; Dossena, S; Patsch, W; Soyal, SM, 2021: Selective Activation of CNS and Reference PPARGC1A Promoters Is Associated with Distinct Gene Programs Relevant for Neurodegenerative Diseases. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 22(7), doi: 10.3390/ijms22073296

2020

• Malcikova, J; Pavlova, S; Vonkova, B; Kotaskova, J; Radova, L; Plevova, K; Zenatova, M; Hynst, J; Dvorackova, B; Panovska, A; Brychtova, Y; Tichy, B; Navrkalova, V; Pal, K; Mayer, J; Doubek, M; Pospisilova, S, 2020: Minor-clone TP53 mutations in CLL patients entering first-line treatment: clonal evolution and clinical impact. LEUKEMIA & LYMPHOMA 61, p. 222 - 224
• Laidou, S; Alanis-Lobato, G; Pribyl, J; Rasko, T; Tichy, B; Mikulasek, K; Tsagiopoulou, M; Oppelt, J; Kastrinaki, G; Lefaki, M; Singh, M; Zink, A; Chondrogianni, N; Psomopoulos, F; Prigione, A; Ivics, Z; Pospisilova, S; Skladal, P; Izsvak, Z; Andrade-Navarro, MA; Petrakis, S, 2020: Nuclear inclusions of pathogenic ataxin-1 induce oxidative stress and perturb the protein synthesis machinery. REDOX BIOLOGY 32, doi: 10.1016/j.redox.2020.101458
• Lobello, C; Tichy, B; Bystry, V; Radova, L; Filip, D; Mraz, M; Montes-Mojarro, IA; Prokoph, N; Larose, H; Liang, HC; Sharma, GG; Mologni, L; Belada, D; Kamaradova, K; Fend, F; Gambacorti-Passerini, C; Merkel, O; Turner, SD; Janikova, A; Pospisilova, S, 2020: STAT3 and TP53 mutations associate with poor prognosis in anaplastic large cell lymphoma. LEUKEMIA , doi: 10.1038/s41375-020-01093-1

2019

• Vecera, M; Sana, J; Oppelt, J; Tichy, B; Alena, K; Lipina, R; Smrcka, M; Jancalek, R; Hermanova, M; Kren, L; Slaby, O, 2019: Testing of library preparation methods for transcriptome sequencing of real life glioblastoma and brain tissue specimens: A comparative study with special focus on long non-coding RNAs. PLOS ONE 14(2), doi: 10.1371/journal.pone.0211978

2018

• Bencurova, P; Baloun, J; Hynst, J; Tichy, B; Pospisilova, S; Kubova, H; Brazdil, M, 2018: Dynamics of Microrna Expression during Early Onset Epileptogenesis. EPILEPSIA 59, p. S58 - S58
• Kubesova, B; Pavlova, S; Malcikova, J; Kabathova, J; Radova, L; Tom, N; Tichy, B; Plevova, K; Kantorova, B; Fiedorova, K; Slavikova, M; Bystry, V; Kissova, J; Gisslinger, B; Gisslinger, H; Penka, M; Mayer, J; Kralovics, R; Pospisilova, S; Doubek, M, 2018: Low-burden TP53 mutations in chronic phase of myeloproliferative neoplasms: association with age, hydroxyurea administration, disease type and JAK2 mutational status. LEUKEMIA 32(2), p. 450 - 461, doi: 10.1038/leu.2017.230
• Gerasimov, ES; Gasparyan, AA; Kaurov, I; Tichy, B; Logacheva, MD; Kolesnikov, AA; Lukes, J; Yurchenko, V; Zimmer, SL; Flegontov, P, 2018: Trypanosomatid mitochondrial RNA editing: dramatically complex transcript repertoires revealed with a dedicated mapping tool. NUCLEIC ACIDS RESEARCH 46(2), p. 765 - 781, doi: 10.1093/nar/gkx1202
• Zaprazna, K; Basu, A; Tom, N; Jha, V; Hodawadekar, S; Radova, L; Malcikova, J; Tichy, B; Pospisilova, S; Atchison, ML, 2018: Transcription factor YY1 can control AID-mediated mutagenesis in mice. EUROPEAN JOURNAL OF IMMUNOLOGY 48(2), p. 273 - 282, doi: 10.1002/eji.201747065
• Brazdilova, K; Plevova, K; Francova, HS; Kockova, H; Borsky, M; Bikos, V; Malcikova, J; Oltova, A; Kotaskova, J; Tichy, B; Brychtova, Y; Mayer, J; Doubek, M; Pospisilova, S, 2018: Multiple productive IGH rearrangements denote oligoclonality even in immunophenotypically monoclonal CLL. LEUKEMIA 32(1), p. 234 - 236, doi: 10.1038/leu.2017.274

2017

• Bencurova, P; Baloun, J; Musilova, K; Radova, L; Tichy, B; Pail, M; Zeman, M; Brichtova, E; Hermanova, M; Pospisilova, S; Mraz, M; Brazdil, M, 2017: MicroRNA and mesial temporal lobe epilepsy with hippocampal sclerosis: Whole miRNome profiling of human hippocampus. EPILEPSIA 58(10), p. 1782 - 1793, doi: 10.1111/epi.13870
• Plesingerova, H; Librova, Z; Plevova, K; Libra, A; Tichy, B; Francova, HS; Vrbacky, F; Smolej, L; Mayer, J; Bryja, V; Doubek, M; Pospisilova, S, 2017: COBLL1, LPL and ZAP70 expression defines prognostic subgroups of chronic lymphocytic leukemia patients with high accuracy and correlates with IGHV mutational status. LEUKEMIA & LYMPHOMA 58(1), p. 70 - 79, doi: 10.1080/10428194.2016.1180690
• Pal, K; Bystry, V; Reigl, T; Demko, M; Krejci, A; Touloumenidou, T; Stalika, E; Tichy, B; Ghia, P; Stamatopoulos, K; Pospisilova, S; Malcikova, J; Darzentas, N, 2017: GLASS: assisted and standardized assessment of gene variations from Sanger sequence trace data. BIOINFORMATICS 33(23), p. 3802 - 3804, doi: 10.1093/bioinformatics/btx423

2016

• Kubesova, B; Pavlova, S; Malcikova, J; Kabathova, J; Radova, L; Tom, N; Tichy, B; Plevova, K; Kantorova, B; Fiedorova, K; Kissova, J; Gisslinger, B; Gisslinger, H; Mayer, J; Kralovics, R; Pospisilova, S; Doubek, M, 2016: Low-Burden TP53 Mutations Occur in Chronic Phase of Myeloproliferative Neoplasms Regardless of Hydroxyurea Administration, Disease Type, and JAK2 Status. BLOOD 128(22)

2015

• Tom, N; Malcikova, J; Radova, L; Kantorova, B; Pardy, F; Pavlova, S; Pal, K; Mraz, M; Tichy, B; Doubek, M; Brychtova, Y; Plevova, K; Mayer, J; Trbusek, M; Pospisilova, S, 2015: MUTATIONS IN THE TP53 GENE SHOW FEATURES OF SOMATIC HYPERMUTATION PROCESS WITH PROMINENT DIFFERENCE BETWEEN IGHV MUTATED AND UNMUTATED CHRONIC LYMPHOCYTIC LEUKEMIA. HAEMATOLOGICA 100, p. 224 - 225
• Kantorova, B; Malcikova, J; Smardova, J; Pavlova, S; Trbusek, M; Tom, N; Plevova, K; Tichy, B; Truong, S; Diviskova, E; Kotaskova, J; Oltova, A; Patten, N; Brychtova, Y; Doubek, M; Mayer, J; Pospisilova, S, 2015: TP53 mutation analysis in chronic lymphocytic leukemia: comparison of different detection methods. TUMOR BIOLOGY 36(5), p. 3371 - 3380, doi: 10.1007/s13277-014-2971-0
• Malcikova, J; Stano-Kozubik, K; Tichy, B; Kantorova, B; Pavlova, S; Tom, N; Radova, L; Smardova, J; Pardy, F; Doubek, M; Brychtova, Y; Mraz, M; Plevova, K; Diviskova, E; Oltova, A; Mayer, J; Pospisilova, S; Trbusek, M, 2015: Detailed analysis of therapy-driven clonal evolution of TP53 mutations in chronic lymphocytic leukemia. LEUKEMIA 29(4), p. 877 - 885, doi: 10.1038/leu.2014.297
• Brazdilova, K; Plevova, K; Francova, HS; Kockova, H; Chmelikova, M; Borsky, M; Burckova, K; Kantorova, B; Tichy, B; Skabrahova, H; Brychtova, Y; Mayer, J; Doubek, M; Pospisilova, S, 2015: Single Cell Analysis of IG Genes in CLL: Cases with Multiple IGH Rearrangements Are Constituted of Several Independent Clones Even When Indistinguishable By Flow Cytometry. BLOOD 126(23)

2013

• Krejci, M; Doubek, M; Brychtova, Y; Stehlikova, O; Chovancova, J; Tichy, B; Francova, HS; Navratil, M; Tomiska, M; Horky, O; Pospisilova, S; Mayer, J, 2013: Fludarabine with cytarabine followed by reduced-intensity conditioning and allogeneic hematopoietic stem cell transplantation in patients with poor-risk chronic lymphocytic leukemia. ANNALS OF HEMATOLOGY 92(2), p. 249 - 254, doi: 10.1007/s00277-012-1579-y
• Khare, V; Lyakhovich, A; Dammann, K; Lang, M; Borgmann, M; Tichy, B; Pospisilova, S; Luciani, G; Campregher, C; Evstatiev, R; Pflueger, M; Hundsberger, H; Gasche, C, 2013: Mesalamine modulates intercellular adhesion through inhibition of p-21 activated kinase-1. BIOCHEMICAL PHARMACOLOGY 85(2), p. 234 - 244, doi: 10.1016/j.bcp.2012.10.026
• Kaucka, M; Plevova, K; Pavlova, S; Janovska, P; Mishra, A; Verner, J; Prochazkova, J; Krejci, P; Kotaskova, J; Ovesna, P; Tichy, B; Brychtova, Y; Doubek, M; Kozubik, A; Mayer, J; Pospisilova, S; Bryja, V, 2013: The Planar Cell Polarity Pathway Drives Pathogenesis of Chronic Lymphocytic Leukemia by the Regulation of B-Lymphocyte Migration. CANCER RESEARCH 73(5), p. 1491 - 1501, doi: 10.1158/0008-5472CAN-12-1752
• Mraz, M; Kozubik, KS; Plevova, K; Musilova, K; Tichy, B; Borsky, M; Kuglik, P; Doubek, M; Brychtova, Y; Mayer, J; Pospisilova, S, 2013: The origin of deletion 22q11 in chronic lymphocytic leukemia is related to the rearrangement of immunoglobulin lambda light chain locus. LEUKEMIA RESEARCH 37(7), p. 802 - 808, doi: 10.1016/j.leukres.2013.03.018

2012

• Doubek, M; Trbusek, M; Malcikova, J; Brychtova, Y; Smardova, J; Lochmanova, J; Panovska, A; Francova, HS; Mraz, M; Tichy, B; Sebejova, L; Navrkalova, V; Plevova, K; Kuglik, P; Mayer, J; Pospisilova, S, 2012: Specific p53 mutations do not impact results of alemtuzumab therapy among patients with chronic lymphocytic leukemia. LEUKEMIA & LYMPHOMA 53(9), p. 1817 - 1819, doi: 10.3109/10428194.2012.658794
• Mraz, M; Dolezalova, D; Plevova, K; Kozubik, KS; Mayerova, V; Cerna, K; Musilova, K; Tichy, B; Pavlova, S; Borsky, M; Verner, J; Doubek, M; Brychtova, Y; Trbusek, M; Hampl, A; Mayer, J; Pospisilova, S, 2012: MicroRNA-650 expression is influenced by immunoglobulin gene rearrangement and affects the biology of chronic lymphocytic leukemia. BLOOD 119(9), p. 2110 - 2113, doi: 10.1182/blood-2011-11-394874
• Janikova, A; Mareckova, A; Dvorakova, D; Bortlicek, Z; Tichy, B; Navratil, M; Kral, Z; Pospisilova, S; Mayer, J, 2012: A real-time (PCR) for a real life ...? Quantitative evaluation of BCL2/IGH in follicular lymphoma and its implications for clinical practice. EXPERIMENTAL HEMATOLOGY 40(7), p. 528 - 539, doi: 10.1016/j.exphem.2012.02.005
• Kostareli, E; Gounari, M; Janus, A; Murray, F; Brochet, X; Giudicelli, V; Pospisilova, S; Oscier, D; Foroni, L; di Celle, PF; Tichy, B; Pedersen, LB; Jurlander, J; Ponzoni, M; Kouvatsi, A; Anagnostopoulos, A; Thompson, K; Darzentas, N; Lefranc, MP; Beless, 2012: Antigen receptor stereotypy across B-cell lymphoproliferations: the case of IGHV4-59/IGKV3-20 receptors with rheumatoid factor activity. LEUKEMIA 26(5), p. 1127 - 1131, doi: 10.1038/leu.2011.311
• Verner, J; Kabathova, J; Tomancova, A; Pavlova, S; Tichy, B; Mraz, M; Brychtova, Y; Krejci, M; Zdrahal, Z; Trbusek, M; Volejnikova, J; Sedlacek, P; Doubek, M; Mayer, J; Pospisilova, S, 2012: Gene expression profiling of acute graft-vs-host disease after hematopoietic stem cell transplantation. EXPERIMENTAL HEMATOLOGY 40(11), p. 899 - 905, doi: 10.1016/j.exphem.2012.06.011
• Agathangelidis, A; Darzentas, N; Hadzidimitriou, A; Brochet, X; Murray, F; Yan, XJ; Davis, Z; van Gastel-Mol, EJ; Tresoldi, C; Chu, CC; Cahill, N; Giudicelli, V; Tichy, B; Pedersen, LB; Foroni, L; Bonello, L; Janus, A; Smedby, K; Anagnostopoulos, A; Merle, 2012: Stereotyped B-cell receptors in one-third of chronic lymphocytic leukemia: a molecular classification with implications for targeted therapies. BLOOD 119(19), p. 4467 - 4475, doi: 10.1182/blood-2011-11-393694
• Kozubik, KS; Malcikova, J; Trbusek, M; Tom, N; Doubek, M; Brychtova, Y; Smardova, J; Mayer, J; Pospisilova, S; Tichy, B, 2012: Clonal Selection of TP53 Mutations in Chronic Lymphocytic Leukaemia Detected by Ultra-deep Pyrosequencing. EUROPEAN JOURNAL OF CANCER 48, p. S146 - S146

2011

• Janikova, A; Tichy, B; Supikova, J; Stano-Kozubik, K; Pospisilova, S; Kren, L; Vasova, I; Salek, D; Mayer, J, 2011: Gene expression profiling in follicular lymphoma and its implication for clinical practice. LEUKEMIA & LYMPHOMA 52(1), p. 59 - 68, doi: 10.3109/10428194.2010.531412
• Lochmanova, J; Mraz, M; Navrkalova, V; Dvorakova, B; Tichy, B; Plevova, K; Sebejova, L; Malcikova, J; Pavlova, S; Benes, V; Rausch, T; Brychtova, Y; Doubek, M; Trbusek, M; Mayer, J; Pospisilova, S, 2011: Mutational Analysis of Mir-29 Family Members in Chronic Lymphocytic Leukemia. BLOOD 118(21), p. 772 - 772
• Mraz, M; Plevova, K; Dolezalova, D; Stano-Kozubik, K; Mayerova, V; Cerna, K; Musilova, K; Pavlova, S; Tichy, B; Lochmanova, J; Doubek, M; Brychtova, Y; Trbusek, M; Hampl, A; Mayer, J; Pospisilova, S, 2011: The Regulation, Targets and Clinical Relevance of Microrna Mir-650 in Chronic Lymphocytic Leukemia (CLL). BLOOD 118(21), p. 1655 - 1656

2010

• Malcikova, J; Tichy, B; Damborsky, J; Kabathova, J; Trbusek, M; Mayer, J; Pospisilova, S, 2010: Analysis of the DNA-binding activity of p53 mutants using functional protein microarrays and its relationship to transcriptional activation. BIOLOGICAL CHEMISTRY 391(2 III), p. 197 - 205, doi: 10.1515/BC.2010.027
• Kotaskova, Jana; Tichy, Boris; Trbusek, Martin; Francova, Hana Skuhrova; Kabathova, Jitka; Malcikova, Jitka; Doubek, Michael; Brychtova, Yvona; Mayer, Jiri; Pospisilova, Sarka, 2010: High Expression of Lymphocyte-Activation Gene 3 (LAG3) in Chronic Lymphocytic Leukemia Cells Is Associated with Unmutated lmmunoglobulin Variable Heavy Chain Region (IGHV) Gene and Reduced Treatment-Free Survival. JOURNAL OF MOLECULAR DIAGNOSTICS 12(3), p. 328 - 334, doi: 10.2353/jmoldx.2010.090100

2009

• Mraz, Marek; Malinova, Karla; Pavlova, Sarka; Tichy, Boris; Kozubik, Katerina Stano; Malcikova, Jitka; Borsky, Marek; Verner, Jan; Doubek, Michael; Brychtova, Yvona; Trbusek, Martin; Mayer, Jiri; Pospisilova, Sarka, 2009: Detail Characterization of 22q11 Deletion and Mir-650 Role in CLL Patients. BLOOD 114(22), p. 507 - 508

• National Center for Medical Genomics, , 2020 - 2022
• Vývoj a testování metody RT-LAMP pro detekci koronaviru v nelaboratorních podmínkách, Masarykova univerzita, 2020 - 2020
• Creating synergies between research infrastructures to stimulate innovation in the cross-border region (ATCZ40), Ministerstvo pro místní rozvoj ČR, 2016 - 2020
• Národní centrum lékařské genomiky (LM2015091), Ministerstvo školství, mládeže a tělovýchovy ČR, 2016 - 2019
• NCLG - Národní centrum lékařské genomiky - modernizace infrastruktury a výzkum genetické variability populace (CZ.02.1.01/0.0/0.0/16_013/0001634), Ministerstvo školství, mládeže a tělovýchovy ČR, 2017 - 2019
• Individuální rozdíly v diferenciaci mezi reprezentací sebe a druhých lidí (GA15-16738S), Grantová agentura ČR, 2015 - 2017
• Understanding empathy using a second person neuroscience approach – a multimodal hyperscanning study combining fMRI and scalp EEG (7AMB15AT015), Ministerstvo školství, mládeže a tělovýchovy ČR, 2015 - 2016
• Expression and function of activation-induced cytidine deaminase splice variants in normal B cell physiology and chronic lymphocytic leukemia (3SGA5792), Jihomoravský kraj, 2013 - 2016
• Functional and structural changes of microRNAs in lymphoproliferative malignancies and their impact on prognosis and prediction of therapy response (NT11218), Ministry of Health - Ministry of Health´s Departmental Research and Development Programme III (2010-2015), 2010 - 2015
• Molekulární charakterizace B buněčných receptorů a jejich vztah k evoluci genetických změn u chronické lymfocytární leukémie, Ministry of Health of the CR, 2012 - 2015
• NGS-PTL - Next Generation Sequencing platform for targeted Personalized Therapy of Leukemia (306242), Evropská unie, 2012 - 2015
• SuPReMMe - Podpora profesního růstu a mezinárodní integrace výzkumných týmů v oblasti molekulární medicíny (CZ.1.07/2.3.00/20.0045), Ministerstvo školství, mládeže a tělovýchovy ČR, 2011 - 2014
• Real-time PCR soupravy pro diagnostiku v onkologii (FR-TI2/254), Ministerstvo průmyslu a obchodu ČR, 2010 - 2013
• Optimalizace metodiky analýzy a hodnocení simultánního EEG-fMRI u pacientů s farmakorezistentní epilepsií (GAP304/11/1318), Grantová agentura ČR, 2011 - 2013
• Functional and molecular characteristics of cancer and normal stem cells - identification of targets for novel therapeutics and therapeutic strategies (MSM0021622430), Ministerstvo školství, mládeže a tělovýchovy ČR, 2007 - 2013
• Involvement of nuclear HMGB proteins in sensitizing of human cells to anticancer drugs inhibiting DNA topoizomerases (GAP301/10/0590), Czech Science Foundation - Standard Grants, 2010 - 2012
• Analysis of changes in genome and its expression in chronic lymphocytic leukemia patients during the disease development (NS10439), Ministry of Health - Departmental Programme of Research and Development (2008-2011), 2009 - 2011