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Head of Core Facility

Main Activity

Scanning probe microscopies for imaging of biological samples - tissue slices, cells, single biomolecules as nucleic acids and proteins. Studies of affinity interactions at the molecular level.

Unique Features

• Visualization and studies of samples using atomic force microscopy (AFM) both in dry state and in liquid

• AFM combined with other techniques: electrochemistry, optical and confocal fluorescence microscopy

• Nanolithography, nanomechanical manipulations, ink-jet based deposition

• Preparation of samples for AFM

• AFM measurements, statistical analysis and data filtration

• Production and bioconjugation of nanoparticles

Key Equipment

• scanning probe microscope - Ntegra Vita / Solaris (NTMDT)

• atomic force microscope NanoWizzard3 (JPK)

• ForceRobot 300 (JPK)

• automated system SolverNEXT (NTMDT)

• ink-jet based deposition system S3 (Scienion)

The Core Facility is part of Czech national centre of European Research Infrastructure Consortium INSTRUCT ERIC under the Czech Infrastructure for Integrative Structural Biology (CIISB) funded by the Ministry of Education, Youth and Sports of the Czech Republic.

 

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