Contact
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| Phone: | +420 54949 5952 |
| Research group: | Chromatin Molecular Complexes - Jiří Fajkus |
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22. Feb. 2021
CEITEC PhD Conference 2021: Doctoral Students from CEITEC are Addressing Major Societal Challenges
The CEITEC PhD Conference is an annual event where doctoral students from CEITEC PhD School present the results of their research. The event is open…
14. Nov. 2017
Students and young scientists have been educated in microscopy within Talking Colors: Advanced Microscopy
The most sophisticated microscopy methods of biomolecular interaction and structure analyses were introduced to young researchers and students in…
Publications that are part of the Web of Science database, possibly also other publications chosen by authors.
2019
- Janovic, T; Stojaspal, M; Veverka, P; Horakova, D; Hofr, C, 2019: Human Telomere Repeat Binding Factor TRF1 Replaces TRF2 Bound to Shelterin Core Hub TIN2 when TPP1 Is Absent. JOURNAL OF MOLECULAR BIOLOGY 431(17), p. 3289 - 3301, doi: 10.1016/j.jmb.2019.05.038
- Veverka, P; Janovic, T; Hofr, C, 2019: Quantitative Biology of Human Shelterin and Telomerase: Searching for the Weakest Point. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 20(13), doi: 10.3390/ijms20133186
2017
- Valuchova, S; Fulnecek, J; Prokop, Z; Stolt-Bergner, P; Janouskova, E; Hofr, C; Riha, K, 2017: Protection of Arabidopsis Blunt-Ended Telomeres Is Mediated by a Physical Association with the Ku Heterodimer. PLANT CELL 29(6), p. 1533 - 1545, doi: 10.1105/tpc.17.00064
- Necasova, I; Janouskova, E; Klumpler, T; Hofr, C, 2017: Basic domain of telomere guardian TRF2 reduces D-loop unwinding whereas Rap1 restores it (gkx812) (vol 45, pg 12170, 2017). NUCLEIC ACIDS RESEARCH 45(21), p. 12599 - 12599, doi: 10.1093/nar/gkx968
- Necasova, I; Janouskova, E; Klumpler, T; Hofr, C, 2017: Basic domain of telomere guardian TRF2 reduces D-loop unwinding whereas Rap1 restores it. NUCLEIC ACIDS RESEARCH 45(21), p. 12170 - 12180, doi: 10.1093/nar/gkx812
2016
- Sepsiova, R; Necasova, I; Willcox, S; Prochazkova, K; Gorilak, P; Nosek, J; Hofr, C; Griffith, JD; Tomaska, L, 2016: Evolution of Telomeres in Schizosaccharomyces pombe and Its Possible Relationship to the Diversification of Telomere Binding Proteins. PLOS ONE 11(4), doi: 10.1371/journal.pone.0154225
2015
- Janouskova, E; Necasova, I; Pavlouskova, J; Zimmermann, M; Hluchy, M; Marini, V; Novakova, M; Hofr, C, 2015: Human Rap1 modulates TRF2 attraction to telomeric DNA. NUCLEIC ACIDS RESEARCH 43(5), p. 2691 - 2700, doi: 10.1093/nar/gkv097
- Dalby, AB; Hofr, C; Cech, TR, 2015: Contributions of the TEL-patch Amino Acid Cluster on TPP1 to Telomeric DNA Synthesis by Human Telomerase. JOURNAL OF MOLECULAR BIOLOGY 427(6), p. 1291 - 1303, doi: 10.1016/j.jmb.2015.01.008
2013
- Buchlovic, M; Kriz, Z; Hofr, C; Potacek, M, 2013: New PAH derivatives functionalized by cyclic nitrone framework: Synthetic design, anti-proliferative activity and interaction with DNA. BIOORGANIC & MEDICINAL CHEMISTRY 21(5), p. 1078 - 1081, doi: 10.1016/j.bmc.2013.01.004
2012
- Kubicek, K; Cerna, H; Holub, P; Pasulka, J; Hrossova, D; Loehr, F; Hofr, C; Vanacova, S; Stefl, R, 2012: Serine phosphorylation and proline isomerization in RNAP II CTD control recruitment of Nrd1. GENES & DEVELOPMENT 26(17), p. 1891 - 1896, doi: 10.1101/gad.192781.112
2011
- Hobor, F; Pergoli, R; Kubicek, K; Hrossova, D; Bacikova, V; Zimmermann, M; Pasulka, J; Hofr, C; Vanacova, S; Stefl, R, 2011: Recognition of Transcription Termination Signal by the Nuclear Polyadenylated RNA-binding (NAB) 3 Protein. JOURNAL OF BIOLOGICAL CHEMISTRY 286(5), p. 3645 - 3657, doi: 10.1074/jbc.M110.158774
2010
- Richard Stefl, Florian C. Oberstrass, Jennifer L. Hood, Muriel Jourdan, Michal Zimmermann, Lenka Skrisovska, Christophe Maris, Li Peng, Ctirad Hofr, Ronald B. Emeson, Frédéric H.-T. Allaine, 2010: The solution structure of the ADAR2 dsRBM-RNA complex reveals a sequence-specific read out of the minor groove. CELL 143(2), p. 225 - 237, doi: 10.1016/j.cell.2010.09.026
2009
- Hofr, C., Sultesova, P., Zimmermann, M., Mozgova, I., Schrumpfova, P. P., Wimmerova, M., Fajkus, J.,, 2009: Single-Myb-histone proteins from Arabidopsis thaliana: a quantitative study of telomere-binding specificity and kinetics. BIOCHEMICAL JOURNAL 419, p. 221 - 228
- Molekulární mechanismus inhibice telomerázy: cílené zastavení dělení nádorových buněk (GA16-20255S), Grantová agentura ČR, 2016 - 2018
- Strukturní a funkční komponenty rostlinných telomer (GA13-06943S), Grantová agentura ČR, 2013 - 2017
- Úloha proteinu Nse, podjednotek komplexu SMC5/6, v procesech stabilizujících pozastavené replikacní vidlice (GA13-00774S), Grantová agentura ČR, 2013 - 2016
- Telomery a stabilita genomu u nižších rostlin (GA13-06595S), Grantová agentura ČR, 2013 - 2015
- Dynamics of shelterin complex assembly (P205/12/0550), Czech Science Foundation - Standard Grants, 2012 - 2015
- Epigenetic mechanisms of plant telomeres regulation (GAP501/11/0569), Czech Science Foundation - Standard Grants, 2011 - 2015
- Ztráta specifických repetic DNA v důsledku dysfunkce CAF1 u rostlin (GAP501/11/0289), Grantová agentura ČR, 2011 - 2015
- Interakční partneři rostlinných telomer a telomeráz (LH13052), Ministerstvo školství, mládeže a tělovýchovy ČR, 2013 - 2015
- Dynamika vzniku shelterinového komplexu, Grantová agentura ČR, 2012 - 2015
- Studium dynamiky telomerových proteinových komplexů zajišťujících stabilitu genomu (LH13054), Ministerstvo školství, mládeže a tělovýchovy ČR, 2013 - 2015
- MODEXBIO - Rozvoj moderních trendů v experimentální biologii: význam biomolekulárních interakcí pro funkci buněčných struktur (CZ.1.07/2.3.00/30.0019), Ministerstvo školství, mládeže a tělovýchovy ČR, 2012 - 2015
- Telomeres and telomerase: transition from molecular to structural biology approach (IAA500040801), Akademie věd ČR, 2008 - 2012