Jakub Hynšt, Ph.D.

Publications that are part of the Web of Science database, possibly also other publications chosen by authors.

2021

• Hynst, J; Navrkalova, V; Pal, K; Pospisilova, S, 2021: Bioinformatic strategies for the analysis of genomic aberrations detected by targeted NGS panels with clinical application. PEERJ 9, doi: 10.7717/peerj.10897
• Bencurova, P; Baloun, J; Hynst, J; Oppelt, J; Kubova, H; Pospisilova, S; Brazdil, M, 2021: Dynamic miRNA changes during the process of epileptogenesis in an infantile and adult-onset model. SCIENTIFIC REPORTS 11(1), doi: 10.1038/s41598-021-89084-9
• Romzova, M; Smitalova, D; Hynst, J; Tom, N; Loja, T; Herudkova, Z; Jurcek, T; Stejskal, L; Zackova, D; Mayer, J; Racil, Z; Culen, M, 2021: Hierarchical distribution of somatic variants in newly diagnosed chronic myeloid leukaemia at diagnosis and early follow-up. BRITISH JOURNAL OF HAEMATOLOGY 194(3), p. 604 - 612, doi: 10.1111/bjh.17659
• Navrkalova, V; Plevova, K; Hynst, J; Pal, K; Mareckova, A; Reigl, T; Jelinkova, H; Vrzatova, Z; Starska, K; Pavlova, S; Panovska, A; Janikova, A; Doubek, M; Kotaskova, J; Pospisilova, S, 2021: LYmphoid NeXt-Generation Sequencing (LYNX) Panel A Comprehensive Capture-Based Sequencing Tool for the Analysis of Prognostic and Predictive Markers in Lymphoid Malignancies. JOURNAL OF MOLECULAR DIAGNOSTICS 23(8), p. 959 - 974, doi: 10.1016/j.jmoldx.2021.05.007

2020

• Malcikova, J; Pavlova, S; Vonkova, B; Kotaskova, J; Radova, L; Plevova, K; Zenatova, M; Hynst, J; Dvorackova, B; Panovska, A; Brychtova, Y; Tichy, B; Navrkalova, V; Pal, K; Mayer, J; Doubek, M; Pospisilova, S, 2020: Minor-clone TP53 mutations in CLL patients entering first-line treatment: clonal evolution and clinical impact. LEUKEMIA & LYMPHOMA 61, p. 222 - 224

2019

• Hynst, J; Plevova, K; Radova, L; Bystry, V; Pali, K; Pospisilova, S, 2019: Bioinformatic pipelines for whole transcriptome sequencing data exploitation in leukemia patients with complex structural variants. PEERJ 7, doi: 10.7717/peerj.7071

2018

• Bencurova, P; Baloun, J; Hynst, J; Tichy, B; Pospisilova, S; Kubova, H; Brazdil, M, 2018: Dynamics of Microrna Expression during Early Onset Epileptogenesis. EPILEPSIA 59, p. S58 - S58

• Individuální rozdíly v diferenciaci mezi reprezentací sebe a druhých lidí (GA15-16738S), Grantová agentura ČR, 2015 - 2017
• Understanding empathy using a second person neuroscience approach – a multimodal hyperscanning study combining fMRI and scalp EEG (7AMB15AT015), Ministerstvo školství, mládeže a tělovýchovy ČR, 2015 - 2016
• Expression and function of activation-induced cytidine deaminase splice variants in normal B cell physiology and chronic lymphocytic leukemia (3SGA5792), Jihomoravský kraj, 2013 - 2016
• Functional and structural changes of microRNAs in lymphoproliferative malignancies and their impact on prognosis and prediction of therapy response (NT11218), Ministry of Health - Ministry of Health´s Departmental Research and Development Programme III (2010-2015), 2010 - 2015
• NGS-PTL - Next Generation Sequencing platform for targeted Personalized Therapy of Leukemia (306242), Evropská unie, 2012 - 2015
• SuPReMMe - Podpora profesního růstu a mezinárodní integrace výzkumných týmů v oblasti molekulární medicíny (CZ.1.07/2.3.00/20.0045), Ministerstvo školství, mládeže a tělovýchovy ČR, 2011 - 2014
• Functional and molecular characteristics of cancer and normal stem cells - identification of targets for novel therapeutics and therapeutic strategies (MSM0021622430), Ministerstvo školství, mládeže a tělovýchovy ČR, 2007 - 2013
• Real-time PCR soupravy pro diagnostiku v onkologii (FR-TI2/254), Ministerstvo průmyslu a obchodu ČR, 2010 - 2013
• Optimalizace metodiky analýzy a hodnocení simultánního EEG-fMRI u pacientů s farmakorezistentní epilepsií (GAP304/11/1318), Grantová agentura ČR, 2011 - 2013
• Involvement of nuclear HMGB proteins in sensitizing of human cells to anticancer drugs inhibiting DNA topoizomerases (GAP301/10/0590), Czech Science Foundation - Standard Grants, 2010 - 2012
• Analysis of changes in genome and its expression in chronic lymphocytic leukemia patients during the disease development (NS10439), Ministry of Health - Departmental Programme of Research and Development (2008-2011), 2009 - 2011