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Research group: | CF: Cryo-Electron Microscopy and Tomography Core Facility |
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6. May 2021
Storage for Science Data by the Most Powerful Supercomputers in Europe Will Be Developed in Ostrava and Brno
The new technology platform is now being developed in Ostrava and Brno, to help with scientific data processing using the most powerful…
27. Apr. 2021
About PhD Studies, Viruses, Cryo-Electron Microscopy and How to Balance Science and Personal Life
Interview with structural virologist Pavol Bardy We often take pride in educating young, globally competitive scientists at our CEITEC PhD School.…
9. Apr. 2021
Letošní Dny elektronové mikroskopie připomínají 70 let od sestrojení prvního přístroje
Dny elektronové mikroskopie zvou již popáté do nanosvěta, a to v termínu od 14. do 18. dubna. Letos si zájemci užijí program především online,…
17. Dec. 2019
EU invests 10 million euro in unlocking technologies for key research in structural biology
Press release, 17. 12. 2019; To enable researchers from European institutes to extend innovative structural biology research, the EU has invested 10…
9. May 2018
Photogallery: 1st Symposium on Recent Advances in Cryo-Electron Microscopy 2018
1st symposium on Recent Advances in Cryo-Electron Microscopy took place at CEITEC MU on April 18–19, 2018. The symposium gathered the…
19. Mar. 2018
Days of Electron Microscopy at CEITEC attracted viewers from all over Brno
Days of Electron Microscopy in Brno aim to present an amazing field of electron microscopy. Within the framework of the event, from 17 March to 23…
Publications that are part of the Web of Science database, possibly also other publications chosen by authors.
2021
- Nagy, B; Polak, M; Ozohanics, O; Zambo, Z; Szabo, E; Hubert, A; Jordan, F; Novacek, J; Adam-Vizi, V; Ambrus, A, 2021: Structure of the dihydrolipoamide succinyltransferase (E2) component of the human alpha-ketoglutarate dehydrogenase complex (hKGDHc) revealed by cryo-EM and cross-linking mass spectrometry: Implications for the overall hKGDHc structure. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1865(6), doi: 10.1016/j.bbagen.2021.129889
- Mukhamedova, L; Fuzik, T; Novacek, J; Hrebik, D; Pridal, A; Marti, GA; Guerin, DMA; Plevka, P, 2021: Virion Structure and In Vitro Genome Release Mechanism of Dicistrovirus Kashmir Bee Virus. JOURNAL OF VIROLOGY 95(11), doi: 10.1128/JVI.01950-20
2020
- Kouba, T; Koval, T; Sudzinova, P; Pospisil, J; Brezovska, B; Hnilicova, J; Sanderova, H; Janouskova, M; Sikova, M; Halada, P; Sykora, M; Barvik, I; Novacek, J; Trundova, M; Duskova, J; Skalova, T; Chon, U; Murakami, KS; Dohnalek, J; Krasny, L, 2020: Mycobacterial HelD is a nucleic acids-clearing factor for RNA polymerase. NATURE COMMUNICATIONS 11(1), doi: 10.1038/s41467-020-20158-4
- Plochberger, B; Sych, T; Weber, F; Novacek, J; Axmann, M; Stangl, H; Sezgin, E, 2020: Lipoprotein Particles Interact with Membranes and Transfer Their Cargo without Receptors. BIOCHEMISTRY 59(45), p. 4421 - 4428, doi: 10.1021/acs.biochem.0c00748
2019
- Bertolla, L; Dlouhy, I; Bartonickova, E; Tousek, J; Novacek, J; Macova, P, 2019: Deconstruction of microfibrillated cellulose into nanocrystalline cellulose rods and mesogenic phase formation in concentrated low-modulus sodium silicate solutions. CELLULOSE 26(7), p. 4325 - 4344, doi: 10.1007/s10570-019-02364-6
- Axmann, M; Sezgin, E; Karner, A; Novacek, J; Brodesser, MD; Rohrl, C; Preiner, J; Stangl, H; Plochberger, B, 2019: Receptor-Independent Transfer of Low Density Lipoprotein Cargo to Biomembranes. NANO LETTERS 19(4), p. 2562 - 2567, doi: 10.1021/acs.nanolett.9b00319
- Kasari, V; Pochopien, AA; Margus, T; Murina, V; Turnbull, K; Zhou, Y; Nissan, T; Graf, M; Novacek, J; Atkinson, GC; Johansson, MJO; Wilson, DN; Hauryliuk, V, 2019: A role for the Saccharomyces cerevisiae ABCF protein New1 in translation termination/recycling. NUCLEIC ACIDS RESEARCH 47(16), p. 8807 - 8820, doi: 10.1093/nar/gkz600
- Nagy, B; Ambrus, A; Zambo, Z; Hubert, A; Polak, M; Szabo, E; Novacek, J; Jordan, F; Adam-Vizi, V, 2019: CRYO-EM STRUCTURE OF THE DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE (E2) COMPONENT OF THE HUMAN ALPHA-KETOGLUTARATE DEHYDROGENASE COMPLEX. PROTEIN SCIENCE 28, p. 155 - 155
- Kezar, A; Kavcic, L; Polak, M; Novacek, J; Gutierrez-Aguirre, I; Znidaric, MT; Co, A; Stare, K; Gruden, K; Ravnikar, M; Pahovnik, D; Zagar, E; Merzel, F; Anderluh, G; Podobnik, M, 2019: Structural basis for the multitasking nature of the potato virus Y coat protein. SCIENCE ADVANCES 5(7), doi: 10.1126/sciadv.aaw3808
2018
- Evangelidis, T; Nerli, S; Novacek, J; Brereton, AE; Karplus, PA; Dotas, RR; Venditti, V; Sgourakis, NG; Tripsianes, K, 2018: Automated NMR resonance assignments and structure determination using a minimal set of 4D spectra. NATURE COMMUNICATIONS 9, doi: 10.1038/s41467-017-02592-z
- Spirek, M; Mlcouskova, J; Belan, O; Gyimesi, M; Harami, G.M; Molnar, E; Novacek, J; Kovacs, M; Krejci, L, 2018: Human RAD51 rapidly forms intrinsically dynamic nucleoprotein filaments modulated by nucleotide binding state. NUCLEIC ACIDS RESEARCH
- Benesik, M; Novacek, J; Janda, L; Dopitova, R; Pernisova, M; Melkova, K; Tisakova, L; Doskar, J; Zidek, L; Hejatko, J; Pantucek, R, 2018: Role of SH3b binding domain in a natural deletion mutant of Kayvirus endolysin LysF1 with a broad range of lytic activity. VIRUS GENES 54(1), p. 130 - 139, doi: 10.1007/s11262-017-1507-2
- Clark, S; Myers, JB; King, A; Fiala, R; Novacek, J; Pearce, G; Heierhorst, J; Reichow, SL; Barbar, EJ, 2018: Multivalency regulates activity in an intrinsically disordered transcription factor. ELIFE 7, doi: 10.7554/eLife.36258
- Sicorello, A; Kelly, G; Oregioni, A; Novacek, J; Sklenar, V; Pastore, A, 2018: The Structural Properties in Solution of the Intrinsically Mixed Folded Protein Ataxin-3. BIOPHYSICAL JOURNAL 115(1), p. 59 - 71, doi: 10.1016/j.bpj.2018.05.029
- Melkova, K; Zapletal, V; Jansen, S; Nomilner, E; Zachrdla, M; Hritz, J; Novacek, J; Zweckstetter, M; Jensen, MR; Blackledge, M; Zidek, L, 2018: Functionally specific binding regions of microtubule-associated protein 2c exhibit distinct conformations and dynamics. JOURNAL OF BIOLOGICAL CHEMISTRY 293(34), p. 13297 - 13309, doi: 10.1074/jbc.RA118.001769
- Plochberger, B; Roehrl, C; Preiner, J; Karner, A; Axmann, M; Novacek, J; Sezgin, E; Eggeling, C; Hinterndorfer, P; Schuetz, GJ; Stangl, H, 2018: INTERACTION OF LIPOPROTEIN PARTICLES WITH LIPID BILAYER-MEMBRANES. ATHEROSCLEROSIS 275, p. E23 - E23, doi: 10.1016/j.atherosclerosis.2018.06.054
- Crowe-McAuliffe, C; Graf, M; Huter, P; Takada, H; Abdelshahid, M; Novacek, J; Murina, V; Atkinson, GC; Hauryliuk, V; Wilson, DN, 2018: Structural basis for antibiotic resistance mediated by the Bacillus subtilis ABCF ATPase VmlR. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 115(36), p. 8978 - 8983, doi: 10.1073/pnas.1808535115
2017
- Huter, P; Arenz, S; Bock, LV; Graf, M; Frister, JO; Heuer, A; Peil, L; Starosta, AL; Wohlgemuth, I; Peske, F; Novacek, J; Berninghausen, O; Grubmuller, H; Tenson, T; Beckmann, R; Rodnina, MV; Vaiana, AC; Wilson, DN, 2017: Structural Basis for Polyproline-Mediated Ribosome Stalling and Rescue by the Translation Elongation Factor EF-P. MOLECULAR CELL 68(3), p. 515 - +, doi: 10.1016/j.molcel.2017.10.014
- Srb, P; Novacek, J; Kaderavek, P; Rabatinova, A; Krasny, L; Zidkova, J; Bobalova, J; Sklenar, V; Zidek, L, 2017: Triple resonance NMR relaxation experiments for studies of intrinsically disordered proteins. JOURNAL OF BIOMOLECULAR NMR 69(3), p. 133 - 146, doi: 10.1007/s10858-017-0138-1
- Skubnik, K; Novacek, J; Fuzik, T; Pridal, A; Paxton, RJ; Plevka, P, 2017: Structure of deformed wing virus, a major honey bee pathogen. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 114(12), p. 3210 - 3215, doi: 10.1073/pnas.1615695114
- Kacirova, M; Novacek, J; Man, P; Obsilova, V; Obsil, T, 2017: Structural Basis for the 14-3-3 Protein-Dependent Inhibition of Phosducin Function. BIOPHYSICAL JOURNAL 112(7), p. 1339 - 1349, doi: 10.1016/j.bpj.2017.02.036
- Jansen, S; Melkova, K; Trosanova, Z; Hanakova, K; Zachrdla, M; Novacek, J; Zupa, E; Zdrahal, Z; Hritz, J; Zidek, L, 2017: Quantitative mapping of microtubule-associated protein 2c (MAP2c) phosphorylation and regulatory protein 14-3-3 zeta-binding sites reveals key differences between MAP2c and its homolog Tau. JOURNAL OF BIOLOGICAL CHEMISTRY 292(16), p. 6715 - 6727, doi: 10.1074/jbc.M116.771097
- PEKAŘÍK, V.; PEŠKOVÁ, M.; GURÁŇ, R.; NOVÁČEK, J.; HEGER, Z.; TRIPSIANES, K.; KUMAR, J.; ADAM, V., 2017: Visualization of stable ferritin complexes with palladium, rhodium and iridium nanoparticles detected by their catalytic activity in native polyacrylamide gels. DALTON TRANSACTIONS 46(40), p. 13690 - 5, doi: 10.1039/c7dt02818k; FULL TEXT
- Lousa, P; Nedozralova, H; Zupa, E; Novacek, J; Hritz, J, 2017: Phosphorylation of the regulatory domain of human tyrosine hydroxylase 1 monitored using non-uniformly sampled NMR. BIOPHYSICAL CHEMISTRY 223, p. 25 - 29, doi: 10.1016/j.bpc.2017.01.003
2016
- Perczel, A; Atanasov, AG; Sklenar, V; Novacek, J; Papouskova, V; Kaderavek, P; Zidek, L; Kozlowski, H; Watly, J; Hecel, A; Kolkowska, P; Koca, J; Svobodova-Varekova, R; Pravda, L; Sehnal, D; Horsky, V; Geidl, S; Enriz, RD; Matejka, P; Jenistova, A; Dendisova, M; Kokaislova, A; Weissig, V; Olsen, M; Coffey, A; Ajuebor, J; Keary, R; Sanz-Gaitero, M; Raaij, MJ; McAuliffe, O; Waltenberger, B; Mocan, A; Smejkal, K; Heis, EH; Diederich, M; Musiol, R; Kosmrlj, J; Polanski, J; Jampilek, J, 2016: The Eighth Central European Conference ´´Chemistry towards Biology´´: Snapshot. MOLECULES 21(10), doi: 10.3390/molecules21101381
- Mullapudi E; Nováček J; Pálková L; Kulich P; Lindberg AM; van Kuppeveld FJ; Plevka P, 2016: Structure and genome release mechanism of human cardiovirus Saffold virus-3. JOURNAL OF VIROLOGY , p. [Epub ahead of print] -
- Nováček J; Šiborová M; Benešík M; Pantůček R; Doškař J; Plevka P, 2016: Structure and genome release of Twort-like Myoviridae phage with a double-layered baseplate. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 113(33), p. 9351 - 6, doi: 10.1073/pnas.1605883113
- Graf M; Arenz S; Huter P; Dönhöfer A; Nováček J; Wilson DN, 2016: Cryo-EM structure of the spinach chloroplast ribosome reveals the location of plastid-specific ribosomal proteins and extensions. NUCLEIC ACIDS RESEARCH , p. [Epub ahead of print] - , doi: 10.1093/nar/gkw1272
- Mullapudi, E; Novacek, J; Palkova, L; Kulich, P; Lindberg, AM; van Kuppeveld, FJM; Plevka, P, 2016: Structure and Genome Release Mechanism of the Human Cardiovirus Saffold Virus 3. JOURNAL OF VIROLOGY 90(17), p. 7628 - 7639, doi: 10.1128/JVI.00746-16
- Kubicek, K; Krejcikova, M; Brazda, P; Smirakova, E; Novacek, J; Cramer, P; Stefl, R, 2016: What are the key aspects of interaction between RNA polymerase II C-terminal domain phosphorylated on tyrosine-1 and the elongation factors. FEBS JOURNAL 283, p. 21 - 21
2015
- MacRaild, CA; Zachrdla, M; Andrew, D; Krishnarjuna, B; Novacek, J; Zidek, L; Sklenar, V; Richards, JS; Beeson, JG; Anders, RF; Norton, RS, 2015: Conformational Dynamics and Antigenicity in the Disordered Malaria Antigen Merozoite Surface Protein 2. PLOS ONE 10(3), doi: 10.1371/journal.pone.0119899
- Kuban, V; Novacek, J; Bumba, L; Zidek, L, 2015: NMR assignment of intrinsically disordered self-processing module of the FrpC protein of Neisseria meningitidis. BIOMOLECULAR NMR ASSIGNMENTS 9(2), p. 435 - 440, doi: 10.1007/s12104-015-9625-z
- Kacirova, M; Novacek, J; Man, P; Kadek, A; Obsilova, V; Obsil, T, 2015: Biophysical characterization of phosducin and its complex with the 14-3-3 protein. PROTEIN SCIENCE 24, p. 124 - 124
2013
- Valencia, RG; Walko, G; Janda, L; Novacek, J; Mihailovska, E; Reipert, S; Andra-Marobela, K; Wiche, G, 2013: Intermediate filament-associated cytolinker plectin 1c destabilizes microtubules in keratinocytes. MOLECULAR BIOLOGY OF THE CELL 24(6), p. 768 - 784, doi: 10.1091/mbc.E12-06-0488
2012
- Novacek, J; Haba, NY; Chill, JH; Zidek, L; Sklenar, V, 2012: 4D Non-uniformly sampled HCBCACON and (1) J(NC alpha)-selective HCBCANCO experiments for the sequential assignment and chemical shift analysis of intrinsically disordered proteins. JOURNAL OF BIOMOLECULAR NMR 53(2), p. 139 - 148, doi: 10.1007/s10858-012-9631-8
- BY COVID, , 2022 - 2025
- IO Software for Exascale Architecture, , 2021 - 2024
- IO Software Environment Architecture (MEYS), , 2021 - 2024
- iNEXT-Discovery: Infrastructure for transnational access and discovery in integrated structural biology (871037), , 2020 - 2024
- EOSC-Life: Providing an open collaborative space for digital biology in Europe, , 2019 - 2023
- Czech Infrastructure for Integrative Structural Biology (LM2018127), MEYS, 2020 - 2022
- CIISB - Česká infrastruktura pro integrativní strukturní biologii pro lidské zdraví (CZ.02.1.01/0.0/0.0/16_013/0001776), Ministerstvo školství, mládeže a tělovýchovy ČR, 2017 - 2021
- Creating synergies between research infrastructures to stimulate innovation in the cross-border region (ATCZ40), Ministerstvo pro místní rozvoj ČR, 2016 - 2020
- Strukturní charakterizace záchrany a recyklace ribozomu, Ministerstvo školství, mládeže a tělovýchovy ČR, 2018 - 2019
- Czech Infrastructure for Integrative Structural Biology (LM2015043), Ministerstvo školství, mládeže a tělovýchovy ČR, 2016 - 2019
- ERC Synergy - Mock Interview, Masarykova univerzita, 2019 - 2019
- iNEXT - Infrastructure for NMR, EM and X-ray crystallography for translational research (653706), Evropská unie, 2015 - 2019
- Příprava ERC Synergy grantu, Masarykova univerzita, 2018 - 2018
- Protein Dynamics Centre (ATCZ26), Ministerstvo pro místní rozvoj ČR, 2016 - 2017
- Structure, maturation and cell entry mechanisms of ranavirus virions (618111), Evropská unie, 2013 - 2015