Jozef Hritz, Ph.D.

Publications that are part of the Web of Science database, possibly also other publications chosen by authors.

2021

• Subadini, S; Bera, K; Hritz, J; Sahoo, H, 2021: Polyethylene glycol perturbs the unfolding of CRABP I: A correlation between experimental and theoretical approach. COLLOIDS AND SURFACES B-BIOINTERFACES 202, doi: 10.1016/j.colsurfb.2021.111696
• Bera, K; Reeda, VSJ; Babila, PR; Dinesh, DC; Hritz, J; Karthick, T, 2021: An in silico molecular dynamics simulation study on the inhibitors of SARS-CoV-2 proteases (3CL(pro) and PLpro) to combat COVID-19. MOLECULAR SIMULATION , doi: 10.1080/08927022.2021.1957884
• Gvarjaladze, D; Gulua, T; Gogichaishvili, S; Hritz, J; Metrevel, N, 2021: Quadruplex Priming Amplification at a Range of Human Body Temperature. BIOINTERFACE RESEARCH IN APPLIED CHEMISTRY 11(1), p. 7932 - 7942, doi: 10.33263/BRIAC111.79327942
• Hofrova, A; Lousa, P; Kubickova, M; Hritz, J; Otasevic, T; Repko, M; Knight, A; Piskacek, M, 2021: Universal two-point interaction of mediator KIX with 9aaTAD activation domains. JOURNAL OF CELLULAR BIOCHEMISTRY , doi: 10.1002/jcb.30075

2020

• Zapletal, V; Mladek, A; Melkova, K; Lousa, P; Nomilner, E; Jasenakova, Z; Kuban, V; Makovicka, M; Lanikova, A; Zidek, L; Hritz, J, 2020: Choice of Force Field for Proteins Containing Structured and Intrinsically Disordered Regions. BIOPHYSICAL JOURNAL 118(7), p. 1621 - 1633, doi: 10.1016/j.bpj.2020.02.019
• Kuban, V; Macek, P; Hritz, J; Nechvatalova, K; Nedbalcova, K; Faldyna, M; Sebo, P; Zidek, L; Bumba, L, 2020: Structural Basis of Ca2+-Dependent Self-Processing Activity of Repeat-in-Toxin Proteins. MBIO 11(2), doi: 10.1128/mBio.00226-20

2019

• Melkova, K; Zapletal, V; Narasimhan, S; Jansen, S; Hritz, J; Skrabana, R; Zweckstetter, M; Ringkjobing Jensen, M; Blackledge, M; Zidek, L, 2019: Structure and Functions of Microtubule Associated Proteins Tau and MAP2c: Similarities and Differences. BIOMOLECULES 9(3), doi: 10.3390/biom9030105
• Precechtelova J P; Mladek, A; Zapletal, V; Hritz, J , 2019: Quantum Chemical Calculations of NMR Chemical Shifts in Phosphorylated Intrinsically Disordered Proteins. JOURNAL OF CHEMICAL THEORY AND COMPUTATION 10(15), p. 5642 - 5658, doi: 10.1021/acs.jctc.8b00257

2018

• Melkova, K; Zapletal, V; Jansen, S; Nomilner, E; Zachrdla, M; Hritz, J; Novacek, J; Zweckstetter, M; Jensen, MR; Blackledge, M; Zidek, L, 2018: Functionally specific binding regions of microtubule-associated protein 2c exhibit distinct conformations and dynamics. JOURNAL OF BIOLOGICAL CHEMISTRY 293(34), p. 13297 - 13309, doi: 10.1074/jbc.RA118.001769
• Jandova, Z; Trosanova, Z; Weisova, V; Oostenbrink, C; Hritz, J, 2018: Free energy calculations on the stability of the 14-3-3 zeta protein. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS 1866(3), p. 442 - 450, doi: 10.1016/j.bbapap.2017.11.012

2017

• Otrusinova, O; Demo, G; Padrta, P; Jasenakova, Z; Pekarova, B; Gelova, Z; Szmitkowska, A; Kaderavek, P; Jansen, S; Zachrdla, M; Klumpler, T; Marek, J; Hritz, J; Janda, L; Iwai, H; Wimmerova, M; Hejatko, J; Zidek, L, 2017: Conformational dynamics are a key factor in signaling mediated by the receiver domain of a sensor histidine kinase from Arabidopsis thaliana. JOURNAL OF BIOLOGICAL CHEMISTRY 292(42), p. 17525 - 17540, doi: 10.1074/jbc.M117.790212
• Nagy, G; Oostenbrink, C; Hritz, J, 2017: Exploring the binding pathways of the 14-3-3ζ protein: Structural and free-energy profiles revealed by Hamiltonian replica exchange molecular dynamics with distancefield distance restraints. PLOS ONE 7(12), doi: 10.1371/journal.pone.0180633
• Jansen, S; Melkova, K; Trosanova, Z; Hanakova, K; Zachrdla, M; Novacek, J; Zupa, E; Zdrahal, Z; Hritz, J; Zidek, L, 2017: Quantitative mapping of microtubule-associated protein 2c (MAP2c) phosphorylation and regulatory protein 14-3-3 zeta-binding sites reveals key differences between MAP2c and its homolog Tau. JOURNAL OF BIOLOGICAL CHEMISTRY 292(16), p. 6715 - 6727, doi: 10.1074/jbc.M116.771097
• Lousa, P; Nedozralova, H; Zupa, E; Novacek, J; Hritz, J, 2017: Phosphorylation of the regulatory domain of human tyrosine hydroxylase 1 monitored using non-uniformly sampled NMR. BIOPHYSICAL CHEMISTRY 223, p. 25 - 29, doi: 10.1016/j.bpc.2017.01.003
• Zapletal, V; Mladek, A; Hritz, J; Zidek, L, 2017: Computational characterization of hybrid proteins containing ordered and intrinsically disordered regions. FEBS JOURNAL 284, p. 321 - 321
• Nagy, G; Oostenbrink, C; Hritz, J, 2017: Exploring the binding pathways of the 14-3-3 zeta : protein Structural and free-energy profiles revealed by Hamiltonian replica exchange molecular dynamics with distancefield distance restraints. PLOS ONE 12(7), doi: 10.1371/journal.pone.0180633
• Melkova, K; Jansen, S; Hritz, J; Zidek, L, 2017: NMR characterization of intrinsically disordered microtubule associated protein 2c. FEBS JOURNAL 284, p. 321 - 322

2015

• Mitra, M; Singer, D; Mano, Y; Hritz, J; Nam, G; Gorelick, RJ; Byeon, IJL; Gronenborn, AM; Iwatani, Y; Levin, JG, 2015: Sequence and structural determinants of human APOBEC3H deaminase and anti-HIV-1 activities. RETROVIROLOGY 12, doi: 10.1186/s12977-014-0130-8

2014

• Gardner, CL; Hritz, J; Sun, CQ; Vanlandingham, DL; Song, TY; Ghedin, E; Higgs, S; Klimstra, WB; Ryman, KD, 2014: Deliberate Attenuation of Chikungunya Virus by Adaptation to Heparan Sulfate-Dependent Infectivity: A Model for Rational Arboviral Vaccine Design. PLOS NEGLECTED TROPICAL DISEASES 8(2), doi: 10.1371/journal.pntd.0002719
• Hritz, J; Byeon, IJL; Krzysiak, T; Martinez, A; Sklenar, V; Gronenborn, AM, 2014: Dissection of Binding between a Phosphorylated Tyrosine Hydroxylase Peptide and 14-3-3 zeta: A Complex Story Elucidated by NMR. BIOPHYSICAL JOURNAL 107(9), p. 2185 - 2194, doi: 10.1016/j.bpj.2014.08.039
• Lui, VWY; Peyser, ND; Ng, PKS; Hritz, J; Zeng, Y; Lu, YL; Li, H; Wang, L; Gilbert, BR; General, IJ; Bahar, I; Ju, ZL; Wang, ZH; Pendleton, KP; Xiao, X; Du, Y; Vries, JK; Hammerman, PS; Garraway, LA; Mills, GB; Johnson, DE; Grandis, JR, 2014: Frequent mutation of receptor protein tyrosine phosphatases provides a mechanism for STAT3 hyperactivation in head and neck cancer. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111(3), p. 1114 - 1119, doi: 10.1073/pnas.1319551111

• Integrative structural biology of pathological tau protein, an appealing therapeutic target for Alzheimer´s disease, , 2020 - 2023
• Selektivní NMR značení jako nástroj pro charakterizaci proteinových komplexů zapojených do neurodegenerativních onemocnění, Ministerstvo školství, mládeže a tělovýchovy ČR, 2019 - 2022
• Characterization of intrinsically disordered proteins, Grantová agentura ČR, 2020 - 2022
• CIISB - Česká infrastruktura pro integrativní strukturní biologii pro lidské zdraví (CZ.02.1.01/0.0/0.0/16_013/0001776), Ministerstvo školství, mládeže a tělovýchovy ČR, 2017 - 2021
• iNEXT - Infrastructure for NMR, EM and X-ray crystallography for translational research (653706), Evropská unie, 2015 - 2019
• Kit pro screening potenciálních léčiv indukujících monomerizaci 14-3-3 (MUNI/71/55952/2016), Masarykova univerzita, 2017 - 2018
• Efektivní výpočty volných energií a konfiguračního vzorkování protein-proteinových interakcí (I 1999-N28), Czech Science Foundation - International Projects, 2015 - 2017
• Podjednotky urcující DNA specificitu bakteriální RNA polymerázy s flexibilními doménami: funkce a dynamika (GA13-16842S), Grantová agentura ČR, 2013 - 2017
• Efektivní výpočty volných energií a konfiguračního vzorkování protein-proteinových interakcí, Grantová agentura ČR, 2015 - 2017
• Design of fluorescence-based analytical tool for quantification of the protein-protein interaction within the 14-3-3 family (7AMB16DE005), Ministerstvo školství, mládeže a tělovýchovy ČR, 2016 - 2017
• Structural determination of the human 14-3-3zeta in complex with a double phosphorylated human tyrosine hydroxylase 1 (4SGA8679), Jihomoravský kraj, 2014 - 2016
• Studium protein-proteinových interakcí pomocí molekulárních simulací (7AMB15AT029), Ministerstvo školství, mládeže a tělovýchovy ČR, 2015 - 2016
• Detailed binding scheme and structural determination of the 14-3-3ζ in complex with a double phosphorylated human tyrosine hydroxylase 1 (618460), Evropská unie, 2013 - 2014