Contact
Email: | , |
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Phone: | +420 54949 3388, +420 54949 5507, +420 54949 3253 |
Research group: | Structural Biology of Gene Regulation - Richard Štefl |
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16. Nov. 2020
Jak mohou kníry vědců z CEITEC zachránit lidský život
Tisková zpráva Víte, že rakovina prostaty patří mezi nejčastější příčiny úmrtí mužů? Jste si jisti, že se netýká právě vás, vašeho…
28. Nov. 2019
Scientists from CEITEC Grew Moustaches Once Again to Support Movember
Press release, 28. 11. 2019; Movember is an annual charity initiative. Its purpose is not only to raise funds, but also to raise awareness of men´s…
Publications that are part of the Web of Science database, possibly also other publications chosen by authors.
2020
- Brazda, P; Krejcikova, M; Kasiliauskaite, A; Smirakova, E; Klumpler, T; Vacha, R; Kubicek, K; Stefl, R, 2020: Yeast Spt6 Reads Multiple Phosphorylation Patterns of RNA Polymerase II C-Terminal Domain In Vitro. JOURNAL OF MOLECULAR BIOLOGY 432(14), p. 4092 - 4107, doi: 10.1016/j.jmb.2020.05.007
- Han, Z; Jasnovidova, O; Haidara, N; Tudek, A; Kubicek, K; Libri, D; Stefl, R; Porrua, O, 2020: Termination of non-coding transcription in yeast relies on both an RNA Pol II CTD interaction domain and a CTD-mimicking region in Sen1. EMBO JOURNAL , doi: 10.15252/embj.2019101548
2019
- Hemzal, D; Kang, YR; Dvorak, J; Kabzinski, T; Kubicek, K; Kim, YD; Humlicek, J, 2019: Treatment of Surface Plasmon Resonance (SPR) Background in Total Internal Reflection Ellipsometry: Characterization of RNA Polymerase II Film Formation. APPLIED SPECTROSCOPY 73(3), p. 261 - 270, doi: 10.1177/0003702819826280
- Brazda, P; Sedo, O; Kubicek, K; Stefl, R, 2019: Efficient and robust preparation of tyrosine phosphorylated intrinsically disordered proteins. BIOTECHNIQUES 67(1), p. 16 - 22, doi: 10.2144/btn-2019-0033
2017
- Jasnovidova, O; Krejcikova, M; Kubicek, K; Stefl, R, 2017: Structural insight into recognition of phosphorylated threonine-4 of RNA polymerase II C-terminal domain by Rtt103p. EMBO REPORTS 18(6), p. 906 - 913, doi: 10.15252/embr.201643723
- Jasnovidova, O; Klumpler, T; Kubicek, K; Kalynych, S; Plevka, P; Stefl, R, 2017: Structure and dynamics of the RNAPII CTDsome with Rtt103. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 114(42), p. 11133 - 11138, doi: 10.1073/pnas.1712450114
2016
- Kubicek, K; Krejcikova, M; Brazda, P; Smirakova, E; Novacek, J; Cramer, P; Stefl, R, 2016: What are the key aspects of interaction between RNA polymerase II C-terminal domain phosphorylated on tyrosine-1 and the elongation factors. FEBS JOURNAL 283, p. 21 - 21
- Jasnovidova, O; Krejcikova, M; Kubicek, K; Stefl, R, 2016: Recognition of phosphorylated threonine-4 of RNA polymerase II C-terminal domain by 3 ´-end processing apparatus. FEBS JOURNAL 283, p. 208 - 209
- Krejcikova, M; Gkionis, K; Hemzal, D; Platts, JA; Papadia, P; Margiotta, N; Sponer, J; Kubicek, K, 2016: Combining NMR (Nuclear Magnetic Resonance) and Raman spectroscopy reveals structural and functional features of a new cisplatin derivative. FEBS JOURNAL 283, p. 164 - 164
2014
- Tudek, A; Porrua, O; Kabzinski, T; Lidschreiber, M; Kubicek, K; Fortova, A; Lacroute, F; Vanacova, S; Cramer, P; Stefl, R; Libri, D, 2014: Molecular Basis for Coordinating Transcription Termination with Noncoding RNA Degradation. MOLECULAR CELL 55(3), p. 467 - 481, doi: 10.1016/j.molcel.2014.05.031
2012
- Sikorsky, T; Hobor, F; Krizanova, E; Pasulka, J; Kubicek, K; Stefl, R, 2012: Recognition of asymmetrically dimethylated arginine by TDRD3. NUCLEIC ACIDS RESEARCH 40(22), p. 11748 - 11755, doi: 10.1093/nar/gks929
- Suchankova, T; Kubicek, K; Kasparkova, J; Brabec, V; Kozelka, J, 2012: Platinum-DNA interstrand crosslinks: Molecular determinants of bending and unwinding of the double helix. JOURNAL OF INORGANIC BIOCHEMISTRY 108, p. 69 - 79, doi: 10.1016/j.jinorgbio.2011.09.025
- Kubicek, K; Cerna, H; Holub, P; Pasulka, J; Hrossova, D; Loehr, F; Hofr, C; Vanacova, S; Stefl, R, 2012: Serine phosphorylation and proline isomerization in RNAP II CTD control recruitment of Nrd1. GENES & DEVELOPMENT 26(17), p. 1891 - 1896, doi: 10.1101/gad.192781.112
2011
- Hobor, F; Pergoli, R; Kubicek, K; Hrossova, D; Bacikova, V; Zimmermann, M; Pasulka, J; Hofr, C; Vanacova, S; Stefl, R, 2011: Recognition of Transcription Termination Signal by the Nuclear Polyadenylated RNA-binding (NAB) 3 Protein. JOURNAL OF BIOLOGICAL CHEMISTRY 286(5), p. 3645 - 3657, doi: 10.1074/jbc.M110.158774
- Kubicek, K; Pasulka, J; Cerna, H; Lohr, F; Stefl, R, 2011: H-1, C-13, and N-15 resonance assignments for the CTD-interacting domain of Nrd1 bound to Ser5-phosphorylated CTD of RNA polymerase II. BIOMOLECULAR NMR ASSIGNMENTS 5(2), p. 203 - 205, doi: 10.1007/s12104-011-9300-y
2010
- Kubicek, K; Grimm, SK; Orts, J; Sasse, F; Carlomagno, T, 2010: The Tubulin-Bound Structure of the Antimitotic Drug Tubulysin. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 49(28), p. 4809 - 4812, doi: 10.1002/anie.200906828
- Kubicek, K; Monnet, J; Scintilla, S; Kopecna, J; Arnesano, F; Trantirek, L; Chopard, C; Natile, G; Kozelka, J, 2010: Unusual Interstrand Pt(S,S-diaminocyclohexane)-GG Crosslink Formed by Rearrangement of a Classical Intrastrand Crosslink Within a DNA Duplex. CHEMISTRY-AN ASIAN JOURNAL 5(2), p. 244 - 247, doi: 10.1002/asia.200900655
- Pergoli, R; Kubicek, K; Hobor, F; Pasulka, J; Stefl, R, 2010: H-1, C-13, and N-15 chemical shift assignments for the RNA recognition motif of Nab3. BIOMOLECULAR NMR ASSIGNMENTS 4(1), p. 119 - 121, doi: 10.1007/s12104-010-9221-1
- DECOR (649030), Evropská unie, 2015 - 2020
- Centrum biologie RNA (GAP305/12/G034), Grantová agentura ČR, 2012 - 2018
- Molekulární podstata pro specifické rozpoznávání histonu H3K4me2 pomocí Set3 PHD domény (GA15-17670S), Grantová agentura ČR, 2015 - 2017
- Zásadní význam fosforylace YS. Studium interakce mezi CTD a transkripčním elongačním faktorem Spt6 (GA15-24117S), Grantová agentura ČR, 2015 - 2017
- Development of new interdisciplinary approaches to study function and regulation of transcriptome, Masarykova univerzita, 2014 - 2016
- Strukturní podstata ukončení transkripce nezávislé na poly(A) signálu (GAP305/10/1490), Grantová agentura ČR, 2010 - 2014
- Structural basis for transcription termination of nonpolyadenylated transcripts (IAA401630903), Akademie věd ČR, 2009 - 2011
- Structural studies of protein-RNA complexes involved in RNA quality control (GA204/08/1212), Howard Hughes Medical Institute, 2008 - 2010
- Structural studies of protein-RNA complexes involved in RNA quality control (1263), Howard Hughes Medical Institute, 2007 - 2009
- Structural studies of protein-RNA interactions involved in RNA quality control (CDA0049/2006), Human Frontier Science Program - Career Development Award, 2007 - 2009