Petra Vychytilová, Ph.D.

Publications that are part of the Web of Science database, possibly also other publications chosen by authors.

2021

• Gregorova, J; Vychytilova-Faltejskova, P; Sevcikova, S, 2021: Epigenetic Regulation of MicroRNA Clusters and Families during Tumor Development. CANCERS 13(6), doi: 10.3390/cancers13061333
• Machackova, T; Vychytilova-Faltejskova, P; Souckova, K; Laga, R; Androvic, L; Mixova, G; Slaby, O, 2021: Barriers in Systemic Delivery and Preclinical Testing of Synthetic microRNAs in Animal Models: an Experimental Study on miR-215-5p Mimic. PHYSIOLOGICAL RESEARCH 70(3), p. 481 - 487, doi: 10.33549/physiolres.934571

2020

• Kondelova, A; Alburquerque-Gonzalez, B; Vychytilova-Faltejskova, P; Garcia-Solano, J; Prochazka, V; Kala, Z; Perez, F; Slaby, O; Conesa-Zamora, P, 2020: miR-181a-2*expression is different amongst carcinomas from the colorectal serrated route. MUTAGENESIS 35(3), p. 233 - 241, doi: 10.1093/mutage/gez039
• Machackova, T; Vychytilova-Faltejskova, P; Souckova, K; Trachtova, K; Brchnelova, D; Svoboda, M; Kiss, I; Prochazka, V; Kala, Z; Slaby, O, 2020: MiR-215-5p Reduces Liver Metastasis in an Experimental Model of Colorectal Cancer through Regulation of ECM-Receptor Interactions and Focal Adhesion. CANCERS 12(12), doi: 10.3390/cancers12123518
• Pichler, M; Rodriguez-Aguayo, C; Nam, SY; Dragomir, MP; Bayraktar, R; Anfossi, S; Knutsen, E; Ivan, C; Fuentes-Mattei, E; Lee, SK; Ling, H; Ivkovic, TC; Huang, GL; Huang, L; Okugawa, Y; Katayama, H; Taguchi, A; Bayraktar, E; Bhattacharya, R; Amero, P; He, WR; Tran, AM; Vychytilova-Faltejskova, P; Klec, C; Bonilla, DL; Zhang, XN; Kapitanovic, S; Loncar, B; Gafa, R; Wang, ZH; Cristini, V; Hanash, SM; Bar-Eli, M; Lanza, GN; Slaby, O; Goel, A; Rigoutsos, I; Lopez-Berestein, G; Calin, GA, 2020: Therapeutic potential of FLANC, a novel primate-specific long non-coding RNA in colorectal cancer. GUT 69(10), p. 1818 - 1831, doi: 10.1136/gutjnl-2019-318903

2019

• Vychytilova-Faltejskova, P; Slaby, O, 2019: MicroRNA-215: From biology to theranostic applications. MOLECULAR ASPECTS OF MEDICINE , doi: 10.1016/j.mam.2019.03.002

2018

• Karasek, P; Gablo, N; Hlavsa, J; Kiss, I; Vychytilova-Faltejskova, P; Hermanova, M; Kala, Z; Slaby, O; Prochazka, V, 2018: Pre-operative Plasma miR-21-5p Is a Sensitive Biomarker and Independent Prognostic Factor in Patients with Pancreatic Ductal Adenocarcinoma Undergoing Surgical Resection. CANCER GENOMICS & PROTEOMICS 15(4), p. 321 - 327, doi: 10.21873/cgp.20090
• Obermannova, R; Redova-Lojova, M; Vychytilova-Faltejskova, P; Grell, P; Cho, WC; Sachlova, M; Svoboda, M; Vyzula, R; Slaby, O, 2018: Tumor Expression of miR-10b, miR-21, miR-143 and miR-145 Is Related to Clinicopathological Features of Gastric Cancer in a Central European Population. ANTICANCER RESEARCH 38(6), p. 3719 - 3724, doi: 10.21873/anticanres.12651
• Kopkova, A; Sana, J; Fadrus, P; Machackova, T; Vecera, M; Vybihal, V; Juracek, J; Vychytilova-Faltejskova, P; Smrcka, M; Slaby, O, 2018: MicroRNA isolation and quantification in cerebrospinal fluid: A comparative methodical study. PLOS ONE 13(12), doi: 10.1371/journal.pone.0208580

2017

• Vychytilova-Faltejskova, P; Merhautova, J; Machackova, T; Gutierrez-Garcia, I; Garcia-Solano, J; Radova, L; Brchnelova, D; Slaba, K; Svoboda, M; Halamkova, J; Demlova, R; Kiss, I; Vyzula, R; Conesa-Zamora, P; Slaby, O, 2017: MiR-215-5p is a tumor suppressor in colorectal cancer targeting EGFR ligand epiregulin and its transcriptional inducer HOXB9. ONCOGENESIS 6, doi: 10.1038/s41389-017-0006-6
• Pichler, M; Stiegelbauer, V; Vychytilova-Faltejskova, P; Ivan, C; Ling, H; Winter, E; Zhang, XN; Goblirsch, M; Wulf-Goldenberg, A; Ohtsuka, M; Haybaeck, J; Svoboda, M; Okugawa, Y; Gerger, A; Hoefler, G; Goel, A; Slaby, O; Calin, GA, 2017: Genome-Wide miRNA Analysis Identifies miR-188-3p as a Novel Prognostic Marker and Molecular Factor Involved in Colorectal Carcinogenesis. CLINICAL CANCER RESEARCH 23(5), p. 1323 - 1333, doi: 10.1158/1078-0432.CCR-16-0497

2016

• Merhautova, J; Vychytilova-Faltejskova, P; Demlova, R; Slaby, O, 2016: Systemic Administration of miRNA Mimics by Liposomal Delivery System in Animal Model of Colorectal Carcinoma. PHYSIOLOGICAL RESEARCH 65, p. S481 - S488
• Iliev, R; Stanik, M; Fedorko, M; Poprach, A; Vychytilova-Faltejskova, P; Slaba, K; Svoboda, M; Fabian, P; Pacik, D; Dolezel, J; Slaby, O, 2016: Decreased expression levels of PIWIL1, PIWIL2, and PIWIL4 are associated with worse survival in renal cell carcinoma patients. ONCOTARGETS AND THERAPY 9, doi: 10.2147/OTT.S91295
• Nemecek, R; Berkovcova, J; Radova, L; Kazda, T; Mlcochova, J; Vychytilova-Faltejskova, P; Slaby, O; Svoboda, M, 2016: Mutational analysis of primary and metastatic colorectal cancer samples underlying the resistance to cetuximab-based therapy. ONCOTARGETS AND THERAPY 9, p. 4695 - 4703, doi: 10.2147/OTT.S102891
• Vychytilova-Faltejskova, P; Pesta, M; Radova, L; Liska, V; Daum, O; Kala, Z; Svoboda, M; Kiss, I; Slaby, O, 2016: Genome-wide microRNA Expression Profiling in Primary Tumors and Matched Liver Metastasis of Patients with Colorectal Cancer. CANCER GENOMICS & PROTEOMICS 13(4), p. 311 - 316
• Kiss, I; Mlcochova, J; Bortlicek, Z; Poprach, A; Drabek, J; Vychytilova-Faltejskova, P; Svoboda, M; Buchler, T; Batko, S; Ryska, A; Hajduch, M; Slaby, O, 2016: Efficacy and Toxicity of Panitumumab After Progression on Cetuximab and Predictive Value of MiR-31-5p in Metastatic Wild-type KRAS Colorectal Cancer Patients. ANTICANCER RESEARCH 36(9), p. 4955 - 4959, doi: 10.21873/anticanres.11063
• Vychytilova-Faltejskova, P; Radova, L; Sachlova, M; Kosarova, Z; Slaba, K; Fabian, P; Grolich, T; Prochazka, V; Kala, Z; Svoboda, M; Kiss, I; Vyzula, R; Slaby, O, 2016: Serum-based microRNA signatures in early diagnosis and prognosis prediction of colon cancer. CARCINOGENESIS 37(10), p. 941 - 950, doi: 10.1093/carcin/bgw078

2015

• Mlcochova, J; Faltejskova-Vychytilova, P; Ferracin, M; Zagatti, B; Radova, L; Svoboda, M; Nemecek, R; John, S; Kiss, I; Vyzula, R; Negrini, M; Slaby, O, 2015: MicroRNA expression profiling identifies miR-31-5p/3p as associated with time to progression in wild-type RAS metastatic colorectal cancer treated with cetuximab. ONCOTARGET 6(36), p. 38695 - 38704
• Lupini, L; Bassi, C; Mlcochova, J; Musa, G; Russo, M; Vychytilova-Faltejskova, P; Svoboda, M; Sabbioni, S; Nemecek, R; Slaby, O; Negrini, M, 2015: Prediction of response to anti-EGFR antibody-based therapies by multigene sequencing in colorectal cancer patients. BMC CANCER 15, doi: 10.1186/s12885-015-1752-5

• Dlouhé nekódující RNA v exozómech jako biomarkery umožňující neinvazivní časnou detekci kolorektálního karcinomu, , 2020 - 2023
• Molecular and functional characterization of colorectal cancer derived-exosomes and exosomal long non-coding RNAs, Grantová agentura ČR, 2020 - 2022
• Národní centrum lékařské genomiky (LM2015091), Ministerstvo školství, mládeže a tělovýchovy ČR, 2016 - 2019
• Analysis of EGFR signalling and microRNA expression profiles in prediction of response to anti-EGFR (NT/13860), Ministry of Health - Ministry of Health´s Departmental Research and Development Programme III (2010-2015), 2012 - 2015
• MicroRNA analysis in glioblastoma stem cells: prediction of therapy response and identification of new therapeutic targets in glioblastoma patients (NT/13514), Ministry of Health - Ministry of Health´s Departmental Research and Development Programme III (2010-2015), 2012 - 2015
• Complex characterization of molecular genetic changes in glioblastoma multiforme and its relapses, and evaluation of their possible significance in oncologic therapy and therapy effect (NT/13581), Ministry of Health - Ministry of Health´s Departmental Research and Development Programme III (2010-2015), 2012 - 2015
• Studium mikroRNA a genů asociovaných s procesem epiteliálně-mezenchymální tranzice jako potenciálních markerů pro predikci rizika a časný záchyt metastazování u pacientů s renálním karcinomem (NT13547-4/2012), Ministry of Health of the CR, 2012 - 2015
• Development of diagnostic panel of circulating microRNAs for non-invasive early diagnostics and follow-up of colorectal cancer patients (NT/13549), Ministry of Health - Ministry of Health´s Departmental Research and Development Programme III (2010-2015), 2012 - 2015
• Development of microRNA diagnostic panel for identification Barret esophagus patients at high-risk of progression to adenocarcinoma (NT13585), Ministry of Health - Ministry of Health´s Departmental Research and Development Programme III (2010-2015), 2012 - 2014
• Identification and functional characterization of microRNAs with predictive significance in patients with glioblastoma (NT/11214), Ministry of Health - Ministry of Health´s Departmental Research and Development Programme III (2010-2015), 2010 - 2013