Tomáš Loja, Ph.D.

Publications that are part of the Web of Science database, possibly also other publications chosen by authors.

2021

• Kolarova, K; Dadejova, MN; Loja, T; Lochmanova, G; Sykorova, E; Dvorackova, M, 2021: Disruption of NAP1 genes in Arabidopsis thaliana suppresses the fas1 mutant phenotype, enhances genome stability and changes chromatin compaction. PLANT JOURNAL 106(1), p. 56 - 73, doi: 10.1111/tpj.15145
• Romzova, M; Smitalova, D; Hynst, J; Tom, N; Loja, T; Herudkova, Z; Jurcek, T; Stejskal, L; Zackova, D; Mayer, J; Racil, Z; Culen, M, 2021: Hierarchical distribution of somatic variants in newly diagnosed chronic myeloid leukaemia at diagnosis and early follow-up. BRITISH JOURNAL OF HAEMATOLOGY 194(3), p. 604 - 612, doi: 10.1111/bjh.17659

2020

• Duskova, L; Nohelova, L; Loja, T; Fialova, J; Zapletalova, P; Reblova, K; Tichy, L; Freiberger, T; Fajkusova, L, 2020: Low Density Lipoprotein Receptor Variants in the Beta-Propeller Subdomain and Their Functional Impact. FRONTIERS IN GENETICS 11, p. 691 - , doi: 10.3389/fgene.2020.00691
• Mancikova, V; Peschelova, H; Kozlova, V; Ledererova, A; Ladungova, A; Verner, J; Loja, T; Folber, F; Mayer, J; Pospisilova, S; Smida, M, 2020: Performance of anti-CD19 chimeric antigen receptor T cells in genetically defined classes of chronic lymphocytic leukemia. JOURNAL FOR IMMUNOTHERAPY OF CANCER 8(1), doi: 10.1136/jitc-2019-000471

2019

• Herudkova, Z; Culen, M; Folta, A; Jeziskova, I; Cerna, J; Loja, T; Tom, N; Smejkal, J; Semerad, L; Dvorakova, D; Mayer, J; Racil, Z, 2019: Clonal hierarchy of main molecular lesions in acute myeloid leukaemia. BRITISH JOURNAL OF HAEMATOLOGY , doi: 10.1111/bjh.16341
• Krafcikova, M; Dzatko, S; Caron, C; Granzhan, A; Fiala, R; Loja, T; Teulade-Fichou, MP; Fessl, T; Hansel-Hertsch, R; Mergny, JL; Foldynova-Trantirkova, S; Trantirek, L, 2019: Monitoring DNA-Ligand Interactions in Living Human Cells Using NMR Spectroscopy. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 141(34), p. 13281 - 13285, doi: 10.1021/jacs.9b03031
• Zaprazna, K; Reblova, K; Svobodova, V; Radova, L; Bystry, V; Baloun, J; Durechova, K; Tom, N; Loja, T; Buresova, M; Stranska, K; Oltova, A; Doubek, M; Atchison, ML; Trbusek, M; Malcikova, J; Pospisilova, S, 2019: Activation-induced deaminase and its splice variants associate with trisomy 12 in chronic lymphocytic leukemia. ANNALS OF HEMATOLOGY 98(2), p. 423 - 435, doi: 10.1007/s00277-018-3520-5

2018

• Culen, M; Kosarova, Z; Jeziskova, I; Folta, A; Chovancova, J; Loja, T; Tom, N; Bystry, V; Janeckova, V; Dvorakova, D; Mayer, J; Racil, Z, 2018: The influence of mutational status and biological characteristics of acute myeloid leukemia on xenotransplantation outcomes in NOD SCID gamma mice. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY 144(7), p. 1239 - 1251, doi: 10.1007/s00432-018-2652-2
• Dzatko, S; Krafcikova, M; Hansel-Hertsch, R; Fessl, T; Fiala, R; Loja, T; Krafcik, D; Mergny, JL; Foldynova-Trantirkova, S; Trantirek, L, 2018: Evaluation of the Stability of DNA i-Motifs in the Nuclei of Living Mammalian Cells. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 57(8), p. 2165 - 2169, doi: 10.1002/anie.201712284

2017

• Dzatko, S; Krafcikova, M; Fiala, R; Fessl, T; Loja, T; Caron, C; Granzhan, A; Fichou, MPT; Mergny, JL; Trantirkova, SF; Trantirek, L, 2017: Cellular structural biology of nucleic acids. FEBS JOURNAL 284, p. 386 - 387
• Kosarova, Z; Culen, M; Jeziskova, I; Folta, A; Chovancova, J; Loja, T; Tom, N; Dvorakova, D; Sustkova, Z; Semerad, L; Racil, Z, 2017: Simulation of AML Clonality in NOD SCID GAMMA Mouse. ANNALS OF HEMATOLOGY 96, p. S61 - S61
• Ondracek, J; Fadrus, P; Sana, J; Besse, A; Loja, T; Vecera, M; Radova, L; Smrcka, M; Slampa, P; Slaby, O, 2017: Global MicroRNA Expression Profiling Identifies Unique MicroRNA Pattern of Radioresistant Glioblastoma Cells. ANTICANCER RESEARCH 37(3), p. 1099 - 1104, doi: 10.21873/anticanres.11422
• Kafkova, LR; Navrkalova, V; Jarosova, M; Loja, T; Chovancova, J; Kucerova, J; Kriegova, E; Prochazka, V; Novak, Z; Simkova, D; Pospisilova, S; Divoky, V, 2017: Ability to downregulate the level of cyclin-dependent kinase inhibitor p27(Kip1) after DNA damage is retained in chronic lymphocytic leukemia cells with functional ATM/p53 signaling pathway. LEUKEMIA & LYMPHOMA 58(1), p. 199 - 203, doi: 10.1080/10428194.2016.1187276
• Dubovy, P; Klusakova, I; Kucera, L; Osiclova, J; Chovancova, J; Loja, T; Mayer, J; Doubek, M; Joukal, M, 2017: Local chemical sympathectomy of rat bone marrow and its effect on marrow cell composition. AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL 206, p. 19 - 27, doi: 10.1016/j.autneu.2017.06.003

2016

• Shyamsunder, P; Esner, M; Barvalia, M; Wu, YJ; Loja, T; Boon, HB; Lleonart, ME; Verma, RS; Krejci, L; Lyakhovich, A, 2016: Impaired mitophagy in Fanconi anemia is dependent on mitochondrial fission. ONCOTARGET 7(36), p. 58065 - 58074, doi: 10.18632/oncotarget.11161

2013

• LOJA, T.;O. STEHLIKOVA;L. PALKO;K. VRBA;I. RAMPL;M. KLABUSAY., 2013: Influence of pulsed electromagnetic and pulsed vector magnetic potential field on the growth of tumor cells. ELECTROMAGNETIC BIOLOGY AND MEDICINE 33(3), p. 190 - 197

2010

• Redova, Martina; Chlapek, Petr; Loja, Tomas; Zitterbart, Karel; Hermanova, Marketa; Sterba, Jaroslav; Veselska, Renata, 2010: Influence of LOX/COX inhibitors on cell differentiation induced by all-trans retinoic acid in neuroblastoma cell lines. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 25(2), p. 271 - 280

• iNEXT-Discovery: Infrastructure for transnational access and discovery in integrated structural biology (871037), , 2020 - 2024
• Creating synergies between research infrastructures to stimulate innovation in the cross-border region (ATCZ40), Ministerstvo pro místní rozvoj ČR, 2016 - 2020
• Národní centrum lékařské genomiky (LM2015091), Ministerstvo školství, mládeže a tělovýchovy ČR, 2016 - 2019
• Profiling DNA structure and DNA ligand interactions inside nuclei of live mammalian cells by in-cell NMR spectroscopy., Masarykova univerzita, 2018 - 2019
• NCLG - Národní centrum lékařské genomiky - modernizace infrastruktury a výzkum genetické variability populace (CZ.02.1.01/0.0/0.0/16_013/0001634), Ministerstvo školství, mládeže a tělovýchovy ČR, 2017 - 2019
• Cellular Structural Biology of non-B DNA Motifs in Human Genome (2535), EMBO (European Molecular Biology Organization), 2013 - 2017
• Cílená terapie proti rezistentím kmenovým buňkám gliomového nádoru - kontrola přísunu živin pomocí iontových kanálů (GA15-20818S), Grantová agentura ČR, 2015 - 2017
• Towards selective targeting of DNA G-quadruplexes by small molecular weight ligands within the human genome (4SGA8580), Jihomoravský kraj, 2014 - 2017
• Evolucne konzervované strukturní vlastnosti centromerické a telomerické DNA (GA13-28310S), Grantová agentura ČR, 2013 - 2016
• Expression and function of activation-induced cytidine deaminase splice variants in normal B cell physiology and chronic lymphocytic leukemia (3SGA5792), Jihomoravský kraj, 2013 - 2016
• Environmentally COntrolled POlymorphism of non-B DNA structures (322104), Evropská unie, 2012 - 2016
• Functional and structural changes of microRNAs in lymphoproliferative malignancies and their impact on prognosis and prediction of therapy response (NT11218), Ministry of Health - Ministry of Health´s Departmental Research and Development Programme III (2010-2015), 2010 - 2015
• Studium mikroRNA a genů asociovaných s procesem epiteliálně-mezenchymální tranzice jako potenciálních markerů pro predikci rizika a časný záchyt metastazování u pacientů s renálním karcinomem (NT13547-4/2012), Ministry of Health of the CR, 2012 - 2015
• Development of diagnostic panel of circulating microRNAs for non-invasive early diagnostics and follow-up of colorectal cancer patients (NT/13549), Ministry of Health - Ministry of Health´s Departmental Research and Development Programme III (2010-2015), 2012 - 2015
• Analysis of EGFR signalling and microRNA expression profiles in prediction of response to anti-EGFR (NT/13860), Ministry of Health - Ministry of Health´s Departmental Research and Development Programme III (2010-2015), 2012 - 2015
• MicroRNA analysis in glioblastoma stem cells: prediction of therapy response and identification of new therapeutic targets in glioblastoma patients (NT/13514), Ministry of Health - Ministry of Health´s Departmental Research and Development Programme III (2010-2015), 2012 - 2015
• Complex characterization of molecular genetic changes in glioblastoma multiforme and its relapses, and evaluation of their possible significance in oncologic therapy and therapy effect (NT/13581), Ministry of Health - Ministry of Health´s Departmental Research and Development Programme III (2010-2015), 2012 - 2015
• NGS-PTL - Next Generation Sequencing platform for targeted Personalized Therapy of Leukemia (306242), Evropská unie, 2012 - 2015
• Development of microRNA diagnostic panel for identification Barret esophagus patients at high-risk of progression to adenocarcinoma (NT13585), Ministry of Health - Ministry of Health´s Departmental Research and Development Programme III (2010-2015), 2012 - 2014
• SuPReMMe - Podpora profesního růstu a mezinárodní integrace výzkumných týmů v oblasti molekulární medicíny (CZ.1.07/2.3.00/20.0045), Ministerstvo školství, mládeže a tělovýchovy ČR, 2011 - 2014
• Identification and functional characterization of microRNAs with predictive significance in patients with glioblastoma (NT/11214), Ministry of Health - Ministry of Health´s Departmental Research and Development Programme III (2010-2015), 2010 - 2013
• Real-time PCR soupravy pro diagnostiku v onkologii (FR-TI2/254), Ministerstvo průmyslu a obchodu ČR, 2010 - 2013
• Functional and molecular characteristics of cancer and normal stem cells - identification of targets for novel therapeutics and therapeutic strategies (MSM0021622430), Ministerstvo školství, mládeže a tělovýchovy ČR, 2007 - 2013
• Involvement of nuclear HMGB proteins in sensitizing of human cells to anticancer drugs inhibiting DNA topoizomerases (GAP301/10/0590), Czech Science Foundation - Standard Grants, 2010 - 2012
• Analysis of changes in genome and its expression in chronic lymphocytic leukemia patients during the disease development (NS10439), Ministry of Health - Departmental Programme of Research and Development (2008-2011), 2009 - 2011